Euglycemic DKA in Patients on SGLT2 Inhibitor and Potentially Ketotic State
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چکیده
منابع مشابه
Euglycemic Diabetic Ketoacidosis in a Patient with Type II Diabetes Mellitus, Ascites and Poor Nutrition on SGLT2 Inhibitor
Title: This is the case of a patient with Euglycemic Diabetic Ketoacidosis (euDKA), ascites, poor nutrition and diabetes mellitus type II on SGLT2 inhibitor. Background: euDKA is an under-reported and under-diagnosed condition that mainly occurs in type I diabetes mellitus patients and in patients with prolonged starvation. The aim of this report is to shed the light on an additional risk facto...
متن کاملEuglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: possible mechanism and contributing factors.
It is possible that SGLT2 inhibitors trigger euglycemic diabetic ketoacidosis in some patients. Possible mechanism of euglycemic DKA induced by SGLT2 inhibitors is illustrated.
متن کاملComment on Rubino et al. Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations. Diabetes Care 2016;39:861-877.
Wereadwith interest the article byRubino et al. (1). The authors suggest treatment withmetabolic surgery after conservative therapy does not reach individual diabetes targets in patients with BMI .30 kg/m. They recommend sodium–glucose cotransporter 2 (SGLT2) inhibitors as suitable drugs, among others, for early postoperative diabetes management due to their low risk of inducing hypoglycemia. T...
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Sodium-glucose cotransporter-2 (SGLT2) inhibitors improve glycemic control by a reversible inhibition of the sodium-glucose cotransporters in the renal proximal tubules resulting in increased urinary glucose. This unique mechanism, independent of insulin secretion and beta cell function, has made this class of medication desirable in patients with type 2 diabetes. However in May 2015, the US Fo...
متن کاملEuglycemic Diabetic Ketoacidosis and Severe Acute Kidney Injury Secondary to off Label Use of Sodium Glucose Cotransporter-2 Inhibitor in a Type-1 Diabetic Patient.
Sodium glucose Cotransporter-2 (SGLT2) inhibitors are a new class of drug approved for the treatment of type-2 diabetes; however they are also increasingly used off label in type-1 diabetic patients. SGLT2 Inhibitors work by increasing glucose excretion in urine. Euglycemic diabetic ketoacidosis (DKA) is potentially life threatening side effect as patients have normal glucose and minimal sympto...
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ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2021
ISSN: 2472-1972
DOI: 10.1210/jendso/bvab048.779